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ArgNPs sustained genome editing with an efficiency of 23 to 30%

These iron ions can exacerbate oxidative stress by catalyzing Fenton and Haber-Weiss reactions, leading to the production of ROS and reactive nitrogen species, which subsequently cause damage to brain cells (Fila et al., 2024)

Reinehr T, Kleber M, Toschke AM, Woelfle J, Roth CL

However, the efficacy shows significant individual differences and scenario dependence

Studies have shown the DAC variant produces a sustained "GH bleed" while the no-DAC variant produces discrete pulses